Category: Network-related events

Winning insights: Prize awarded to researchers investigating a new potential drug target for Chagas disease

Our huge congratulations go to Dr Daniele Chame (above), post-doctoral research associate from the Federal University of Minas Gerais (UFMG), Brazil, and Carlos Estevez, a masters’ student at UFMG, co-recipients of the 2019 Zigman Brener award at the XXXV Annual Meeting of the Brazilian Society for Protozoology (SBPz).   Daniele and Carlos, two of our NTD Network early career researchers from Professor Santuza Teixeira’s team at UFMG, Belo Horizonte, presented their findings as a poster in the Translational Biology session during the meeting, held this year in Caxambu, Brazil, 4th-6th November.  Daniele accepted the prize alone, as Carlos was at our “Workshop in Drug Discovery” training and industry symposium, held in Mendoza, Argentina, 2nd-4th November.   … Continue reading
Durham-FAPESP SPRINT colleagues

Seeing further: A Brazil-UK collaboration to shine light on the mysteries of parasite cell membranes

“If I have seen further, it has been through standing on the shoulders of giants” (John of Salisbury, 1159).
NTD Network partners and colleagues from Durham, UK and universities from across Sao Paulo state in Brazil gathered this week at Durham University to launch an inter-institutional sister collaboration, investigating transmembrane proteins from neglected tropical diseases (NTDs) and other infectious agents.  The FAPESP-SPRINT initiative project is a joint venture between the UK’s Biotechnology and Biological Sciences Research Council (BBSRC) and Brazil’s Fundação de Amparo a Pesquisa do Estado de São Paulo (FAPESP).  Membrane proteins hold huge potential as drug targets, yet are poorly understood, this ‘invisibility’ due to the technical challenges of working with these often insoluble proteins.  This collaboration, between Durham University, the University of São Paulo (USP) and the Brazilian Biosciences National Laboratory (LNBio), combines the cross-disciplinary expertise from all three institutions.  The team plan to develop a suite of tools for characterising the membranes of living cells, equipping us to ‘see further’ in our search for new drug targets for Chagas disease, leishmaniasis and other NTDs.

 

Second CGID meeting in Newcastle: Sharing enthusiasm and insights for infectious diseases research

The second Centre for Global Infectious Diseases (CGID) annual meeting, a joint venture Durham University and the University of Newcastle, took place today at the Newcastle Medical School, hosted by our colleagues from the Newcastle University Fungal Research team.  This year’s programme showcased some of the engaging research into global infections that takes place across the northeast UK, and gave particular emphasis to early career researchers working on globally-significant diseases, many of which impact developing countries.  … Continue reading

Off the well-trodden path: Ribeirão Preto’s forest offers diverse potential new drug solutions

Prior to delivering a workshop at the University of São Paolo (USP) Ribeirão Preto campus, UK Network members Patrick Steel, Paul Denny, Ehmke Pohl and colleagues from USP and Durham University, spent a day exploring.  The Serra da Canastra national park in Minas Gerais, the origin of the São Francisco river, is home to a tropical and scrubby forest, known to these scientists as USP professor Noberto Lopes’ “chemical hunting ground”.  The workshop, “Development and evaluation of bioactive compounds” (March 25th-29th 2019; funded by Brazil’s Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) ‘SPRINT’ initiative), equipped ~40 Brazilian postgraduate students with skills to source novel chemicals from plants, fungi and animals.  USP’s natural products library already holds many naturally-sourced compounds new to science, but more are needed – as leads for new medicines to treat the Neglected Tropical Diseases (NTDs) affecting Brazil and other developing countries.  On this hot day, the team veer off a well-trodden path to go exploring in the forest, taking in spectacular waterfalls and an impromptu swim.

… Continue reading