February 20th, 2019, and Dr Julia Cricco (right) gathers her research team at the National University of Rosario (UNR), Argentina, to greet the new arrival; a small, grey box… This unremarkable-looking machine is a ‘Nucleofector’ from Lonza, purchased with Equipment Fund support from the Global Network for Neglected Tropical Diseases (NTDs). This device will transform the speed at which Julia’s group can progress towards identifying valid biological targets for developing new drugs against Chagas disease. The arrival of this one small box is therefore much celebrated, provoking excitement and big smiles all round!