Centre for Immunology and Infection in the Department of Biology at the University of York
Dr. Pegine Walrad is a Research Lecturer in Molecular Parasitology appointed to the Centre for Immunology and Infection in the Department of Biology at the University of York. Training as a zoologist and veterinary nurse, Pegine explored fly and yeast genetics at Stony Brook University then shifted to molecular parasitology examining gene regulation in Trypanosomatids at the University of Edinburgh. Notably, she characterised the first trans-regulator of a surface antigen and a novel pathway of mRNA nuclear export in Trypanosoma brucei. Her current research focuses upon regulators of Leishmania differentiation to human-infectious forms and has recently identified the mRNA binding and whole cell proteomes of Leishmania mexicana, the RNA binding protein targets of the first methylating enzyme implicated in Leishmania spp. parasite virulence and the swimming dynamics of distinct promastigote stages with support from an MRC New Investigator Research Grant, two joint Newton/MRC UK-Brazil Neglected Infectious Diseases grants, BBSRC, Wellcome and participation in two MRC Global Challenges Research Fund consortiums.